In stock
Part Number | SKU
253591

Cummins QSX 15 | DEF Header | 4352100C91

Special Price $373.00 Regular Price $9,999.00

Brand-new aftermarket DEF header, no core needed. Direct OEM replacement for 4352100C91 & more. Built to OEM specs and backed by manufacturer warranty.

DEF Header | 4352100C91

Restore your truck’s emissions system with this brand-new aftermarket DEF header, a direct-fit replacement for OEM part number 4352100C91. No core charge. No hassle. Built to meet stringent OEM standards, this DEF header offers reliable performance and seamless compatibility across a wide range of diesel applications.

Designed for Navistar and Cummins QSX engines, this header replaces multiple OEM references including 2523591C91, 4140918C91, 4097728C91, and 4254210C91. Whether you’re servicing a fleet or a single truck, this DEF header ensures accurate DEF level and temperature readings to prevent fault codes and maintain full emissions compliance.

Constructed with high-quality materials for durability and resistance to urea corrosion, this header installs easily with OEM-style connectorsno modifications required. It’s the ideal solution for truck shops, fleet managers, and owner-operators looking to reduce downtime and avoid dealership markups.

Backed by a manufacturer warranty, this replacement DEF header delivers long-term value and performance you can trust.

Upgrade today and keep your truck running clean, compliant, and on the road with a cost-effective, emissions-ready DEF header replacementno core required, from American Radiator.

DEF Header Features:

Designed to meet or exceed OEM specifications
Aftermarket no core charge
2-year/40,000 miles/1200 hours manufacturer warranty (whichever comes first)

Designed For:

Navistar International
Cummins QSX15

Manufacturer Warranty

DuraWRX provides a manufacturer's warranty on its DEF-related products for up to 2 years/40,000 miles/1,200 hours (whichever occurs first). This warranty covers any defects in materials or workmanship. To be eligible for a claim, the end user must register their product purchase on the DuraWRX site. To file a claim, customers must contact DuraWRX to receive a return shipping label. Once the product is returned and the claim is approved, DuraWRX will issue either a refund or a credit.

DEF Header Specs

DEF Header Height: 25"
DEF Return Fitting: 5/16"
Coolant Outlet Fitting: 5/8"
Tank Interface: 6 Bolt
Electrical Connector: Deutsch DT4
Sensor Type: Digital
DEF Suction Fitting: 3/8"
Coolant Inlet Fitting: 5/8"
In-Tank Filter: 40 Micron

Please confirm your OEM or Aftermarket number matches before ordering.

4352100C91  
2523591C91  
4140918C91  
4097728C91  
4254210C91  
2517604C1  
4086046C91  
2515987C1  
2515986C1  
2510966C3  
2510966C1 

Shipping & Returns

Famous Same-Day Shipping: In-stock items typically ship the same day when ordered by 3 PM CST Monday through Friday

Why Buy From American Radiator?

Trust American Radiator, your reliable source for quality cooling solutions since 2001. With roots in the industry dating back to the 1970s, our team brings decades of experience delivering high-performance radiators, charge air coolers, and DPF systems at competitive prices.

We work directly with trusted domestic and international manufacturers that supply OEM-grade components, ensuring every product meets or exceeds original equipment standards. Whether you need a heavy-duty truck radiator or a replacement for your DEF Header, we’re committed to providing durable, cost-effective solutions that perform.

Have questions? Contact our experienced inside sales team at 888-483-5763 for expert guidance and fast, friendly support.

More Information
Part Number | SKU 253591
OEM | Aftermarket Numbers 4352100C91 2523591C91 4140918C91 4097728C91 4254210C91 2517604C1 4086046C91 2515987C1 2515986C1 2510966C3 2510966C1 ASP9082321623 ASP-908-2321-623

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